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Specifically, Concerns were raised for several figures in this article, including panels of Figs 3A, 3B, 3C, 4B, 4F, 4G, 5B and S1B. Figs 2B, 2C, 3A, 3B, 3C, 4B, 4F, 4G, 5B and S1B. The authors have provided data from replicate experiments in the S1B File of the article, given that original files were not available for assessment in a number of instances and the integrity issues surrounding the preparation of Fig 2B, the PLOS Biology Editors remain concerned about the integrity.

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About NSABP Foundation The NSABP Foundation, Inc, an academic research organization, conducts industry-supported cancer research in new chemotherapeutic and targeted biologic agents for evaluation in adjuvant and neoadjuvant clinical trials (PALOMA-1, PALOMA-2, PALOMA-3), 1. Grade 3 or 4 neutropenia. The trial is sponsored by the GBG as part of a clinical research collaboration with other study groups.

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